Skip to main content

22 OLD FEMALE WITH INTERMITTENT FEVERS SINCE 1 YEAR, URINARY INCONTINENCE SINCE 1 DAY

  This is an online E-log entry blog to discuss and understand the clinical data analysis of a patient, to develop competency in comprehending clinical problems, and providing evidence- based inputs in order to come up with a diagnosis and effective treatment plan to the best of my ability.


Mentioned here are my learning points, both theoretical and practical surrounding this patient:

-I performed a full sensory and motor system examination on this patient and recorded my findings below. Additionally, I learnt how to localize the level of spinal cord lesion based on my findings. Beaver's sign was a learning point for me as well.

-Learnt how to differentiate LMN bladder from UMN type bladder

-Learnt about NMOSD (Neuromyelitis Optica Spectrum Disorder), its symptoms and possible clinical findings



The patient came to the OPD with chief complaints of:

-Urinary retention since 1 day


HISTORY OF PRESENTING ILLNESS:

Patient was apparently asymptomatic 1 year back when she developed headache, fever and acute urinary retention. Following the development of these complaints, she came to our hospital where she was evaluated and diagnosed with transverse myelitis. 

The evaluation along with the blog contents of the previous admission at our college have been added here below:

(Courtesy of Vasishta: https://vasishta175.blogspot.com/2022/02/admission-3-and-6-amc-bed-1-patient.html?m=1 )

Patient was brought to casualty with c/o :-

-Headache since 10 days

-Fever since 10 days

-Acute urinary retention since 5 days


22yr old female , farmer by occupation 

Patient was apparently asymptomatic 10 days back , then she developed a headache, diffuse in nature, occipital region predominantly, gradual in onset , dragging type , radiating to neck, aggravated on talking , rotating the head , relieved on medication 

Associated with nausea

- Phonophobia present 

- No h/o Photophobia , Lacrimation

- C/o Fever since 10 days , High grade fever associated with chills and rigors, Continuous , relieved on medication , gradual in onset 

- Pt c/o Vomitings , associated with nausea , Non projectile , not associated with blood 

- After 5 days Pt c/o urinary retention ( acute ) , able to feel fullness of bladder , not able to pass urine , relieved after passing foleys 

-No c/o cold , cough 

- 5 days back Pt attenders c/o Altered Sensorium which lasted for 5 mins . Not able to recognise persons , place, time 

- Had Weakness of lower limbs for 4 days . Spontaneously resolved . 

- patient was not able to walk on her own during the weakness episode 

- No seizures , weakness 





Ophthalmology referral:- 


Impression:- 

Early changes of Papillodema noted ( Grade 1)


Personal history:- 

Married female 

Appetite - decreased , improved since yesterday 

Bowels- Constipation , relieved on medication 

Micturition- abnormal 

Addictions:- No addiction

General examination:-

Pt is c/c/c

Pallor present

No icterus , cyanosis , clubbing , odema, lymphadenopathy 

Vitals:-

Temp:- Afebrile

PR:- 110bpm

RR:- 14 /min

BP:- 100/60mmhg

Spo2:- 97%

GRBS:- 133mg%


Systemic examination:- 

CVS :- S1S2 heard , No murmurs 

RS:- BAE present 

PA:- Soft, Non tender 

CNS:- Intact

           Neck stiffness:- No 

           Kernig sign :- No


    Reflexes        Right        Left

   Biceps.        Absent.    Absent 

   Triceps             1+              1+

  Supinator.         1+.             1+

   Knee.                2+.             2+

   Ankle.               1+.             1+

   Plantar.           Mute.        Mute

     


    Tone :-         Right.        Left

 Upper limb.      Normal.  Normal

Lower limb.      Normal.   Normal 


   Power:-        Right            Left

 Upper limb.     5/5.               5/5

 Lower limb.      5/5.              5/5


- No finger nose in coordination 

- No knee - heel in coordination


GAIT VIDEO:-

https://youtube.com/shorts/aOUKlG0NHu8?feature=share


LUMBAR PUNCTURE DONE ON 17/02/22

https://youtu.be/LC1zkDCWLpI

https://youtu.be/YUpvRrfq86E


INVESTIGATIONS:- 

Hemogram:-

Hb:- 13.3gm/dl

TC:- 9,200

N/L/E/M/B:- 80/15/03/02/00

MCV:- 81.1

MCHC:- 34.7

RBC count:- 4.7 millions

Platelets :- 4.3 lakhs

Aptt:- 35sec

Bleeding time :- 2min 

Clotting time :- 4 min 30 sec

Prothrombin time :- 18

 INR :- 1.3

RBS:- 114mg/dl

LFT:-

TB:- 0.81

DB:- 0.20

AST :- 28

ALT:- 18

AlP:- 96

TP:- 7.0

A/G Ratio:- 1.48

RFT:-

Urea :- 27

Creatinine :- 0.7

Na :- 141

K:- 4.4

Cl:- 97


CSF ANALYSIS:- 

Sugar:- 74mg/dl

Protein:- 27mg/dl

Chloride:- 118mmol/L

TC:- 25 cells

DC:- 100% L

RBC - Nil

                 Chest X ray:-


MRI SPINE DONE ON 18/2/22





Impression :-

Longitudinal extensive transverse myelitis ( C3 to conus medullaris) 
To rule out :- 
- NMO/ Demyelination 
- Anti MOG antibody disease 
- GFAP astrocytopathy
- Sarcoidosis/ SLE


Treatment plan:

-Inj DEXA 2cc IV STAT

-Inj CEFTRIAXONE 2gm IV/ STAT

-Inj OPTINEURON 1amp in 100ml NS IV/OD

-Inj Mannitol 20gm/ 100ml IV/ STAT


DURING CURRENT ADMISSION (27/6/2023):

Since the patient got discharged 1 year ago, she has been having intermittent fevers, 1-2 episodes a month,  low grade, occasionally associated with chills and rigors. During these episodes, she would take Tab. DOLO 650mg, following which the fever would subside. The fever was not associated with nausea, vomiting. 

She had intermittent episodes of  headaches as well, usually during fever episodes but sometimes without fever as well, diffuse in nature, dull aching type, sometimes radiating to neck, with no aggravating factors. Patient noted that the headache was relieved after she wore her spectacles. Her headache was not associated with photophobia, phonophobia, lacrimation.

She also had tingling in both her lower limbs uptil thighs, intermittent in nature but not specifically associated with her fever. The tingling also did not have any aggravating or relieving factors as such. It was also accompanied by occasional dragging type pain in both lower limbs, non radiating in nature.

She had  acute urinary retention since 1 day. She last passed urine around 1 am last night, following which she was unable to pass urine, even though she was able to feel fullness of her bladder. Retention was relieved after passing Foley's- she voided around 500ml. 

She had an abortion 6 months ago, 3 months into her pregnancy. That was the only time she visited a hospital in the last year.


PAST HISTORY

She had an LSCS 3 years ago  

No history of HTN, CVD, CAD, thyroid, TB, asthma, epilepsy


MARITAL AND OBSTETRIC HISTORY

The patient had a second degree consanguinous marriage at 16 years of age. 6 months into her marriage she conceived, following which she had a spontaneous abortion in the first trimester. The doctor had said that fetal heart rate was not heard.

After 2 years she conceived again after using medication for conception. This time she had a miscarriage in the second trimester due to ? situs inversus.

After 6 months she conceived again, this time to term. She gave birth to a live healthy baby who is now 3 years old.

After 2 years she conceived again, this time also she had a miscarriage in her first trimester due to absent fetal heart beat.


PERSONAL HISTORY: 

Diet - mixed

Sleep - Disturbed since 1 year

Appetite - Decreased since 1 year, especially during fever episodes

Bowel and bladder - regular

No addictions

No allergies  


PSYCHOSOCIAL HISTORY:

Patient is 22 years old 

She studied till 10th grade, after which she got married at 15 years. She has been married since 7 years now, and has one 3 year old daughter. She works as a farmer, along with her husband who is also a farmer. She lives with her husband, daughter and mother-in-law.

Her daily routine consists of her waking up at 5.30am, preparing breakfast and eating around 9am. Her family usually eats rice or idli for breakfast. Following this, she goes for work at the fields or does household work until lunch which is at 1pm- patient eats rice for lunch. In the afternoons, she takes care of the buffaloes, and later comes back in the evening and prepares dinner which she eats around 8pm- usually rice and curry. She sleeps around 9pm.

However, she patient mentioned that she had been unable to sleep properly since several months, due to unknown reasons. She would wake up 2-3 times in the night and be unable to fall asleep again. 

During her fever episodes also, she continues to work as well as take care of her daughter. Additionally, most of the household work is done by the patient even during fever episodes, as her mother-in-law has knee pain and hence has trouble walking. The patient felt that the fever episodes were a burden on her as she would have to continue working despite feeling lethargic and tired during these episodes.

She was initially worried 1 year ago getting fever episodes as she was worried that her myelitis would flare up again. However, she is no longer too anxious about this.


FAMILY HISTORY: 

No significant history  


GENERAL EXAMINATION: 

Patient is conscious, coherent and co-operative.

She is moderately built and moderately nourished.

                                           

                                           

                                           

Pallor - Absent

Icterus - Absent

Cyanosis - Absent 

Clubbing - Absent 

No lymphadenopathy

Pedal edema- Absent


Vitals : 

Temperature - 96.8 ° F

Blood Pressure -120/70 mmHg

Pulse Rate -78 bpm

Respiratory Rate - 13 cpm


Current gait in comparison to her gait during previous admission:

Gait from previous admission:

https://youtube.com/shorts/aOUKlG0NHu8?feature=share


Gait from current admission:





SYSTEMIC EXAMINATION: 

CNS EXAMINATION:

HIGHER MENTAL FUNCTIONS

Normal

Memory intact


CRANIAL NERVES-

Normal


Neck stiffness:- No 

Kernig sign :- No


SENSORY EXAMINATION

                                 Right          Left

Spinothalamic

Crude touch              +                      +

Pain                          +                      +       

Temperature             +                      +


Dorsal column

Fine touch              Lost in bilateral soles

Vibration

Olecranon p            6s                        5s

Styloid process       7s                        10s

Tibia                        4s                        8s

Medial mallelous     6s                        10s



MOTOR EXAMINATION

    Reflexes        Right        Left

   Biceps.              +                 +

   Triceps             +                 +

  Supinator.           -                -

   Knee.                ++             ++

   Ankle.               ++             ++

   Plantar.            Flexor      Flexor

 

T11-12 Reflexes absent    

Beaver's sign negative


    Tone :-         Right.        Left

 Upper limb.      Normal.  Normal

Lower limb.      Normal.   Normal 


   Power:-        Right            Left

 Upper limb.     5/5.               5/5

 Lower limb.      5/5.              5/5


Lower limb examination in detail, done to localise anatomy of lesion:

   Power:-                                             Right            Left

HIPS 

ILEOPSOAS (L1-L3)                           5/5                 5/5

ADDUCTOR FEMORIS (L5-S1)         4-/5                 4-/5

G MAXIMUS (L5-S1)                          4-/5                 4-/5

G MEDIUS, MINIMUS (L2-L3)           4-/5                 4-/5


THIGH

HAMSTRINGS (L4-S1)                          4-/5                 4-/5

QUADRICEPS (L3-L4)                           4+/5                 4+/5


ANKLE

TIBIALIS ANTERIOR (L4-L5)                4-/5                 4-/5

TIBIALIS POSTERIOR (L4)                    4-/5                 4-/5

PERONEI (L5, S1)                                    4-/5                 4-/5

GASTROCNEMIUS (S1)                          4-/5                 4-/5


FOOT, GREAT TOE 

EXT. DIG. LONGUS (L5)                4-/5                 4-/5

FL. DIG. LONGUS (S1, S2)             4+/5                 4+/5

EXT. HAL. LONGUS (L5, S1)          4-/5                 4-/5

EXT. DIG. BREVIS (S1)                    4-/5                 4-/5


- No finger nose in coordination 

- No knee - heel in coordination


PER ABDOMINAL EXAMINATION:

INSPECTION

Suprapubic bulge +

Umbilicus : inverted 

All quadrants of abdomen move with respiration 

No visible peristalsis, pulsations, sinuses

PALPATION-

Abdomen soft

No local rise of temperature 

Suprapubic bulge + non tender, relieved after Foley's catheterisation

No organomegaly

PERCUSSION:

Resonance note heard over all quadrants

AUSCULTATION:

Bowel sounds heard  


 

CVS EXAMINATION: S1, S2 heard; no murmurs

RS EXAMINATION: BAE+, Normal Vescicular breath sounds heard



PROVISIONAL DIAGNOSIS: 

LMN Type Neurogenic Bladder

?Recurrent Transverse Myelitis

?Neuromyelitis Optica Spectrum Disorder


EVALUATION: 

Hemogram:

Hb: 9.3 gm%

TLC: 6700

PCV: 29.8

MCV: 71.0

MCH: 22.1

MCHC: 31.2

RBCs: 4.20 millions/cumm

PLT: 3.63 laks/cumm


ANA PROFILE- negative


ECG:

                                            

                                            

USG abdomen:

                                            


Neurology referral was done for this patient:

Ophthalmology referral done for this patient (fundoscopy attached):
                                       


Treatment plan:
1. INJ METHYL PREDNISOLONE 1GM IN 100ML NS OVER 1 HOUR IV OD X 5 DAYS
2. INJ PAN 40MG IV OD BBF AT 8AM
3. TAB AZORAN 25MG PO OD AT 2PM
4. E/O LUBREX 5 TIMES DAILY X 5 DAYS
FOLEY'S CATHETARISATION WAS DONE FOR THIS PATIENT AND REMOVED ON DAY 6 OF ADMISSION AS SHE WAS ABLE TO PASS URINE SPONTANEOUSLY (DAY 4 OF INJ PREDNOSOLONE)

ADVICE AT DISCHARGE:
TAB WYSOLONE 30MG PO OD AT 2PM FOR 7 DAYS
TAB AZATHIOPRINE 25MG PO OD AT 2PM FOR 7 DAYS
TAB PAN 40MG PO OD AT 7AM BEFORE BREAKFAST FOR 3 DAYS



Comments

Popular posts from this blog

50 YEAR OLD FEMALE WITH FEVER, LEFT LOIN PAIN

   This is an online E-log entry blog to discuss and understand the clinical data analysis of a patient, to develop competency in comprehending clinical problems, and providing evidence- based inputs in order to come up with a diagnosis and effective treatment plan to the best of my ability. Mentioned here are my learning points, both theoretical and practical surrounding this patient: -Taking psychosocial and past history of this patient was particularly eye opening. She had several hospital admissions in the last 2 years with 3 for pyelonephritis alone. Her history made me realize the hardships of patients with chronic health conditions, and the pain that both her and her family would have to suffer from it. -I also got to learn the pathophysiology of PAH and how to causes murmurs. Additionally, I got to appreciate the murmurs in this patient as well. -An interesting medical dilemma surrounding this patient was whether or not to give IV fluids. 2D ECHO showed a collapsing IVC along w

22 Y/O FEMALE WITH RASHES, FACIAL PUFFINESS

 This is an online E-log entry blog to discuss and understand the clinical data analysis of a patient, to develop competency in comprehending clinical problems, and providing evidence- based inputs in order to come up with a diagnosis and effective treatment plan to the best of my ability. A 22 year old female, R/O Nakrekal, currently a student, came with the chief complaints of 1. Rashes all over her body since 5 days 2. Facial puffiness since 3 days HISTORY OF PRESENTING ILLNESS The patient was apparently asymptomatic 1 month back when she developed rashes over her legs and arms and abdomen after contact with something in her family's lemon field. For this, they visited a local doctor the next day, who prescribed her steroid ointment (halobetasol propionate) and oral medication, which she took for 10 days. The rashes subsided, however, blackish discoloration remained over the skin.  10 days back she developed fever which was high grade, intermittent in nature, associated chills a

90 Y/O WITH SWELLING OF TONGUE

  This is an online E-log entry blog to discuss and understand the clinical data analysis of a patient, to develop competency in comprehending clinical problems, and providing evidence- based inputs in order to come up with a diagnosis and effective treatment plan to the best of my ability. A 90 year old female, R/O yerramguda came with the chief complaints of: 1. Slurring of speech since 1 day 2. Swelling of tongue since 1day 3. Fever since 1day The patient was apparently asymtomatic 3 months back when she developed fever, which was high grade, associated with chills and rigors, and decreased on taking medication. The fever subsided after 4 days. Along with the fever, she also developed redness in the mouth, with no other symptoms as mentioned by her.  2 months ago, she slipped on the bathroom and fell, which caused a fracture to get right femur. Surgery was done for it at our hospital, and she started walking around with the help of support. She still continues to do so.  1 day ago,